Beyond the Architecture:
Why Global Health Still Needs Hope
Dr. José M. Zuniga, President/CEO, Fast-Track Health
Dr. Richard Horton’s recent Lancet essay, “The Tragic Fallacy of Global Health Reform,” is characteristically unsettling and largely correct. Drawing on Jorge Luis Borges’s fictional world of Tlön, Dr. Horton warns that global health reformers may be constructing an elaborate new order on paper while mistaking its coherence for reality. Commissions are established, diagrams drawn, and declarations issued. But the forces that govern the real world – power, money, national interest, institutional survival, and entrenched dependency – remain stubbornly intact.
Global health is not primarily an architectural problem; it is a problem of power. Institutions rarely surrender authority, resources, or relevance voluntarily. Donor governments embrace the language of “country ownership” while continuing to determine priorities, control financing, and define acceptable evidence. International organizations endorse localization while protecting their own mandates and operating models. Philanthropies and development agencies speak of partnership while retaining the power to decide which problems matter, which solutions are fundable, and whose expertise counts.
The Lancet’s Editor-in-Chief is right to challenge the comforting fiction that a better organizational chart will, by itself, produce justice. Renaming institutions, consolidating mechanisms, or creating new coordinating bodies cannot correct inequity if the underlying distribution of power remains unchanged. Reform that leaves low- and middle-income countries dependent on external financing, imported expertise, and donor-defined metrics while preserving the same hierarchies of authority, is merely institutional rearrangement.
The present crisis makes that critique especially urgent. Development assistance is contracting. As I chronicle in my book Aftershocks, multilateralism is under strain, nationalism is displacing solidarity, and the political consensus that once sustained global health cooperation has fractured. Programs that took decades to build can be weakened by a single budget, election, or executive decision. Against that backdrop, promises of a redesigned global health system can sound detached from political reality and even dangerously consoling.
Yet realism must not harden into resignation. Hope is not a denial of power. Properly understood, it is a decision to confront power without accepting its present distribution as permanent. Indeed, every meaningful advance in global health – from smallpox eradication to the HIV response – was once dismissed as unrealistic, unaffordable, or politically impossible. Progress occurred because communities organized, scientists persisted, governments were pressured, resources were mobilized, and institutions were forced to change.
The HIV response offers perhaps the clearest lesson. Millions of people did not gain access to antiretroviral therapy (ART) because those holding power spontaneously yielded it charitably. Activists converted moral outrage into political pressure. People living with HIV insisted that lived experience was expertise. Countries challenged pricing structures and intellectual property orthodoxies. Clinicians, researchers, community organizations, and political leaders built coalitions that made the previously “impossible” unavoidable.
That is the kind of hope global health needs now: not optimism without evidence, but disciplined hope. Disciplined hope names injustice accurately, identifies who benefits from the status quo, and measures reform by the transfer of decision-making authority, resources, and accountability. It recognizes that regional, national, and municipal institutions must have the fiscal space, technical capacity, and political authority to lead. It also insists that communities are co-authors and governors of health systems.
This approach asks harder questions. Who sets priorities? Who controls data? Who owns knowledge? Who receives the money? Who is accountable when commitments are broken? And does a proposed reform reduce dependency, or simply modernize its language? We should therefore heed Dr. Horton’s warning without accepting hopelessness as its inevitable conclusion. The choice is not between naïve idealism and fatalism; it is between reform as performance and reform as a sustained contest over power.
The future of global health will not be secured by drawing a more elegant map of institutions, nor will it be protected by surrendering to the world as it is. The late Dr. Jonathan Mann, creator of the first Global AIDS Programme at the World Health Organization (WHO), urged us to challenge “the inherited so-called ‘natural’ order of things and continually “call the status quo into question.” We must remain clear-eyed about the obstacles and equally clear about our obligation to overcome them. Aspiration without action becomes illusion, but action without aspiration becomes mere crisis management.
Our task is not to invent Tlön or to retreat from the possibility of a more just world. Instead, it is to build that world in the difficult terrain of reality, one deliberate act of transformation at a time: country by country, city by city, institution by institution, and community by community. Hope must not substitute for power; it must help us organize to redistribute it and transform aspiration into lasting change.

